ZAN<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\n\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t<\/div><\/div><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tWELCOME to the ZAN project!<\/strong><\/p>ZAN \u2013 Acquired hearing loss in the Zebrafish model: investigating the mechanisms underlying Aging and Noise effects on the vertebrate auditory system<\/span><\/strong><\/p>\u6591\u99ac\u9b5a\u6a21\u578b\u7684\u807d\u529b\u640d\u5931\uff1a\u8001\u5316\u4ee5\u53ca\u566a\u97f3\u5728\u810a\u690e\u52d5\u7269\u7684\u807d\u89ba\u7cfb\u7d71\u88f9\u5f71\u97ff\u6a5f \u5236\u7684\u63a2\u8a0e<\/p><\/div><\/div>
Objectives: This project aims to 1) to examine the cellular and molecular mechanisms underlying noise induced hearing loss; 2) to investigate the genetic modulation of age-related hearing loss; and 3) to evaluate how aging and exposure to noise interact causing hearing dysfunction in the zebrafish model. <\/span><\/p>Relying on a variety of\u00a0electrophysiology,\u00a0immunohistochemistry, imaging, genetic and and behavioral techniques. this project provides an opportunity to gain a comprehensive knowledge on the underlying mechanisms of auditory dysfunction in vertebrates. The team will focus on<\/span>\u00a0two main types of acquired hearing impairment and their interaction at the structure and function levels, which is fundamental for a sensible design of protective measures and treatment of human deafness.<\/span><\/p>Project reference:\u00a0<\/span>FDCT 046\/2018\/A2 (2018-2022)
<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\tTEAM<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tRaquel O. Vasconcelos<\/a><\/strong><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t![\"\"](\"https:\/\/ise.usj.edu.mo\/wp-content\/uploads\/2018\/11\/Raquel-pic-150x150.png\")
\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tPrincipal Investigator\u00a0(PI),\u00a0ISE, USJ, Macau<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tMiguel Godinho Ferreira\u00a0<\/a><\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t![\"\"](\"https:\/\/ise.usj.edu.mo\/wp-content\/uploads\/2020\/04\/Miguel-Ferreira-IRCAN-150x150.jpg\")
\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tTeam member –\u00a0<\/span>Institute of Research on Cancer and Aging of Nice, France (IRCAN ), and Champalimaud Center for the Unknown, Portugal<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tDong Liu<\/strong><\/span><\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t![\"\"](\"https:\/\/ise.usj.edu.mo\/wp-content\/uploads\/2020\/04\/Dong-Liu-SUSTech-150x150.jpg\")
\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tTeam member, Southern University of Science and Technology, China (SUSTech)<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tFlora Gordillo-Martinez<\/strong><\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t![\"\"](\"https:\/\/ise.usj.edu.mo\/wp-content\/uploads\/2020\/04\/Flora-MArtinez-150x150.jpeg\")
\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tPostdoctoral researcher, ISE, USJ, Macau<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tRafael A. Lara<\/strong><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t![\"\"](\"https:\/\/ise.usj.edu.mo\/wp-content\/uploads\/2020\/04\/Rafael-Lara-150x150.png\")
\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\tPhD student, ISE, USJ, Macau<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\n\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\n\t\t\t\t\t\t\t
WELCOME to the ZAN project!<\/strong><\/p> ZAN \u2013 Acquired hearing loss in the Zebrafish model: investigating the mechanisms underlying Aging and Noise effects on the vertebrate auditory system<\/span><\/strong><\/p> \u6591\u99ac\u9b5a\u6a21\u578b\u7684\u807d\u529b\u640d\u5931\uff1a\u8001\u5316\u4ee5\u53ca\u566a\u97f3\u5728\u810a\u690e\u52d5\u7269\u7684\u807d\u89ba\u7cfb\u7d71\u88f9\u5f71\u97ff\u6a5f \u5236\u7684\u63a2\u8a0e<\/p><\/div><\/div> Objectives: This project aims to 1) to examine the cellular and molecular mechanisms underlying noise induced hearing loss; 2) to investigate the genetic modulation of age-related hearing loss; and 3) to evaluate how aging and exposure to noise interact causing hearing dysfunction in the zebrafish model. <\/span><\/p> Relying on a variety of\u00a0electrophysiology,\u00a0immunohistochemistry, imaging, genetic and and behavioral techniques. this project provides an opportunity to gain a comprehensive knowledge on the underlying mechanisms of auditory dysfunction in vertebrates. The team will focus on<\/span>\u00a0two main types of acquired hearing impairment and their interaction at the structure and function levels, which is fundamental for a sensible design of protective measures and treatment of human deafness.<\/span><\/p> Project reference:\u00a0<\/span>FDCT 046\/2018\/A2 (2018-2022) Raquel O. Vasconcelos<\/a><\/strong><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t Principal Investigator\u00a0(PI),\u00a0ISE, USJ, Macau<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t Miguel Godinho Ferreira\u00a0<\/a><\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t Team member –\u00a0<\/span>Institute of Research on Cancer and Aging of Nice, France (IRCAN ), and Champalimaud Center for the Unknown, Portugal<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t Dong Liu<\/strong><\/span><\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t Team member, Southern University of Science and Technology, China (SUSTech)<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t Flora Gordillo-Martinez<\/strong><\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t Postdoctoral researcher, ISE, USJ, Macau<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t Rafael A. Lara<\/strong><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t PhD student, ISE, USJ, Macau<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\tTEAM<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
![\"\"](\"https:\/\/ise.usj.edu.mo\/wp-content\/uploads\/2020\/04\/Vivian-Wong-1-150x150.jpeg\")
\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t![\"\"](\"https:\/\/ise.usj.edu.mo\/wp-content\/uploads\/2020\/04\/Yolanda-Lau-150x150.jpeg\")
\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t