Flora Gordillo-Martinez
POST-DOCTORAL RESEARCHER
Research Gate: Flora Gordillo-Martinez
E-mail: flora.gordillo@usj.edu.mo
EDUCATION:
- 2009 BSc (Hons) in Biology, specialization in Molecular Biology
- 2012 MSc in Biomedical Research
- 2014 PhD in Molecular Biology and Biomedicine
ACADEMIC PROFESSIONAL EXPERIENCE:
2008 to 2009, Student internship in the Department of Microbiology at Biology School, University of Seville
2010 to 2015, PhD student and Lecturer in the Department of Cytology and Histology Normal and Pathological at Medicine School, University of Seville
2016 to 2017, Postdoctoral researcher in the State Key Laboratory of Quality Research in Chinese Medicine at Macau University of Science and Technology
2018 to 2019, Postdoctoral researcher in the Institute of Cardiovascular Disease at School of Basic Medical Sciences, Guangzhou Medical University
RESEARCH INTERESTS
Currently, my research focuses on Age-related of Hearing Loss in the zebrafish model.
SELECTED PUBLICATIONS
- Chen, Z. *; Gordillo-Martinez, F. *; Jiang, L.; He, P.; Hong, W.; Wei, X.; Staines, K.A.; Macrae, V.E.; Zhang, C.; Yu, D.; Fu, X.; and Zhu, D. Zinc ameliorates human aortic valve calcification through GPR39 mediated ERK1/2 signaling pathway. Cardiovascular Research. 2020 Apr 7. [*co-first author]
- Qu, Y.Q.*, Gordillo-Martinez, F.*, Law, B.Y.K., Han, Y., Wu, A., Zeng, W., Lam, W.K., Ho, S.W.F., He, H.Q., Wong, V.K.W., Wang, R. (2018) 2-Aminoethoxydiphenylborane sensititizes anti-tumor effect of bortezomib via supperssion of calcium-mediated autophagy. Cell Death & Disease. Mar 2; 9(3):361. [*co-first author]
- Mok, S.W.F.; Zeng, W.; Niu, Y.; Coghi, P.; Wu, Y.; Sin, W.M.; Ng, S.I.; Gordillo-Martínez, F.; Gao, J.Y.; Law, B.Y.K.; Liu, L.; Yao, X.; and Wong, V.K.W. A Method for Rapid Screening of Anilide-Containing AMPK Modulators Based on Computational Docking and Biological Validation. Frontiers in Pharmacology. 2018 Jul 3;9:710.
- de Seabra Rodrigues Dias, I.R.; Mok, S.W.F.; Gordillo-Martínez, F.; Khan, I.; Hsiao, W. W. L.; Law, B.Y.K.; Wong, V.K.W.; and Liu, L. The Calcium-Induced Regulation in the Molecular and Transcriptional Circuitry of Human Inflammatory Response and Autoimmunity. Frontiers in Pharmacology. 2018 Jan 8;8:962.
- Law, B.Y.K.; Gordillo-Martínez, F.; Qu, Y.Q.; Zhang, N.; Xu, S.W.; Coghi, P.S.; Mok, S.W.F.; Guo, J.; Zhang, W.; Leung, E.L.H.; Fan, X.X.; Wu, A.G.; Chan, W.K.; Yao, X.J.; Wang, J.R.; Liu, L. and Wong, V.K.W. Thalidezine, A Novel AMPK Activator, Eliminates Apoptosis-resistant Cancer Cells Through Energy-mediated Autophagic Cell Death. Oncotarget. 2017 May 2;8(18):30077-30091.
- Law, B.Y.K.; Qu, Y.Q.; Mok, S.W.F.; Liu, H.; Zeng, W.; Han, Y.; Gordillo-Martinez, F.; Chan, W.; Wong, K.M.; and Wong, V.K.W. New perspectives of cobalt tris(bipyridine) system: anti-cancer effect and its collateral sensitivity towards multidrug-resistant (MDR) cancers. Oncotarget. 2017. 8(33): p. 55003-55021.
- Utrilla, J.C. *; Gordillo-Martínez, F. *; Gómez-Pascual, A.; Fernández-Santos, J.M.; Garnacho, C.; Vázquez-Román, V.; Morillo-Bernal, J.; García-Marín, R.; Jiménez-García, A. and Martín-Lacave, I. Comparative study of the primary cilia in thyrocytes of adult mammals. Journal of Anatomy. 2015 Oct; 227(4):550-60. [*co-first author]
- García-Marín, R.; Fernández-Santos, J.M.; Morillo-Bernal, J.; Gordillo-Martínez, F.; Vázquez-Román, V.; Utrilla, J.C.; Carrillo-Vico, A.; Guerrero, J.M. and Martín-Lacave, I. Melatonin in the thyroid gland: regulation by thyroid-stimulating hormone and role in thyroglobulin gene expression. Journal of Physiology and Pharmacology. 2015 Oct; 66(5):643-52.
- Utrilla, J.C.; Morillo-Bernal, J.; Gordillo-Martínez, F.; García-Marín, R.; Herrera, J.L.; Fernández-Santos, J.M.; Díaz-Parrado, E.; Garnacho, C.; De Miguel, M. and Martín-Lacave, I. Expression of hypothalamic regulatory peptides in thyroid C cells of different mammals. General and Comparative Endocrinology. 2013 Jun 15; 187:6-14.
- Morillo-Bernal, J.; Fernández-Santos, J.M.; De Miguel, M.; García-Marín, R.; Gordillo-Martínez, F.; Díaz-Parrado, E.; Utrilla, J.C. and Martín-Lacave, I. Ghrelin potentiates TSH-induced expression of the thyroid tissue-specific genes thyroglobulin, thyroperoxidase and sodium-iodine symporter, in rat PC-Cl3 Cells. Peptides. 2011 Nov; 32(11):2333-9.
SELECTED COMMUNICATIONS
- Acquired sensorineural hearing loss: from noise to aging effects on zebrafish. Man Ieng Wong, Ieng Hou Lau, Flora Gordillo-Martínez, Paulo J. Fonseca, Raquel O. Vasconcelos. THE 7TH ANNUAL MEETING OF THE SOCIETY FOR BIOACOUSTICS 4 DECEMBER 2020.
- The impact of temporal variation in noise exposure on anxiety-related behavior and hearing in the adult zebrafish. Man Ieng Wong, Ieng Hou Lau, Flora Gordillo-Martínez, Paulo J. Fonseca, Raquel O. Vasconcelos. XVII CONGRESSO DA SOCIEDADE PORTUGUESA DE ETOLOGIA (SPE) 6 November 2020.
- Age-Related Hearing Loss in the Zebrafish model: investigating the mechanisms underlying aging sensory loss, synaptopathy and morphological correlates. Man Ieng Wong, Flora Gordillo-Martínez, Ieng Hou Lau, Paulo J. Fonseca, Raquel O. Vasconcelos. 11TH EUROPEAN ZEBRAFISH MEETING 26-27 OCTOBER 2020