Sara Cardoso
POST-DOCTORAL RESEARCHER
e-mail: sara.cardoso@usj.edu.mo
EDUCATION:
- 2009 BSc in Biology, specialization in Evolutionary and Developmental Biology
- 2011 MSc in Bioinformatics and Computational Biology
- 2019 PhD in Biological Sciences, specialization in Molecular Ecology
- 2013 to 2018, PhD student in the Integrative Behavioural Biology Lab at the Instituto Gulbenkian de Ciência (IGC), Oeiras, Portugal.
- 2019 to Present, Postdoctoral fellow at the Institute of Science and Environment.
RESEARCH INTERESTS
Broadly, I seek to understand the proximate mechanisms underlying the expression of behavior, specifically the ones that facilitate consistent patterns of behavior within populations/strains of the same species. During my PhD, I focused my research on sexual behavior and developmental plasticity, where I investigated the neural and molecular mechanisms that regulated the observed plasticity in behavior in natural populations by doing RNA-seq. I am interested in how sexual conflict is resolved in a system where both males and females display different levels of aggression due to either natural or artificial selection. Additionally, the genomic basis of aggression in this species is being researched using different approaches from hormonal to genomic analyses by comparing the described strains. More recently, my research interests spanned to behavioral changes due to micro and nanoplastic pollution, and how these are mediated by differences in gene expression at different developmental stages.
Genomic and physiological mechanisms of aggressive behaviour; Transcriptomics of intralocus sexual conflict; Genome editing using the CRISPR tool kit; microplastic pollution
SELECTED RESEARCH PROJECTS
PlastiFish: Methods, effects and risk analysis of microplastics in fish production/ 漁類生產中的微塑料檢測方法,影響及風險分析. FDCT-FCT 0004/2019/APJ, 2020-2023 (Co-PI).
FISHMUC-Bioactive properties of external mucus isolated from coastal fish of Macao and Portugal/ 澳門及葡萄牙沿海魚類外部黏液的生物活性特徵. FDCT-FCT 0005/2019/APJ, 2020-2023 (team member).
FIGHT – Hormonal, pheromonal and genomic regulation of aggression in a fish model” 決鬥– 魚模型的攻擊性以荷爾蒙、費洛蒙及基因之調控. FDCT0093/2017/A2, 2017-2020 (team member).
SELECTED PUBLICATIONS
- Gonçalves D, Fusani B, Cardoso SD & Canário AVM (2024). Hormones and Sexual Behavior of Teleost Fishes (Chapter 7), Hormones and Reproduction of Vertebrates, Volume 1, Academic Press, in press.
The work had the support of the Macao Science and Technology Development Fund (FDCT), project 0025/2020/A2, and SDC was supported by the postdoctoral fellowship FDCT0001/2021/APD. We thank Alexandre Lebel for providing the Betta splendens drawings.
- Alex D, Cardoso SD, Ramos A & Gonçalves D (2023). Behavioural and endocrine responses to non-interactive live and video conspecifics in males of the Siamese fighting fish. Current Zoology 69: 568–577. https://doi.org/10.1093/cz/zoac078
Acknowledgements:
This work was supported by the Macao Science and Technology Development (FDCT) fund through projects 093/2017/A2 and 0025/2017/A2, and postdoctoral fellowships FDCT0003/2019/APD and FDCT0001/2021/APD awarded to SDC.
- Ramos A, Alex D, Cardoso SD & Gonçalves D (2021). Androgens and corticosteroids increase in response to mirror images and interacting conspecifics in males of the Siamese fighting fish Betta splendens. Hormones and Behavior 132: 104991. doi:10.1016/j.yhbeh.2021.104991
Acknowledgements:
This work was supported by the Macao Science and Technology Development Fund (FDCT), project 093/2017/A2. SDC was supported by the postdoctoral fellowship FDCT0003/2019/APD. We thank two anonymous reviewers and the Associate Editor for their insightful comments on a previous version of the manuscript.
- Félix AS, Cardoso SD, Roleira A and Oliveira RF (2020). Forebrain transcriptional response to transient changes in circulating androgens in a cichlid fish. G3: Genes, Genomes, Genetics 10: 1971–1982. doi:10.1534/g3.119.400947.
- Cardoso SD, Gonçalves D, Goesmann A, Canário AVM and Oliveira RF (2018). Temporal variation in brain transcriptome is associated with the expression of female mimicry as a sequential male alternative reproductive tactic in fish. Molecular Ecology 27: 789-803. doi: 10.1111/mec.14408
- Fan G, Chan J, Ma K, Yang B, Zhang H, Yang X, Shi C, Law H, Ren Z, Xu Q, Liu Q, Wang J, Chen W, Shao L, Gonçalves D, Ramos A, Cardoso SD, Guo M, Cai J, Xu X, Wang J, Yang H, Liu X, Wang Y (2018). Chromosome-level reference genome of the Siamese fighting fish Betta splendens, a model species for the study of aggression. GigaScience. doi: 10.1093/gigascience/giy087
- Cardoso SD, Faustino AI, Costa SS, Valério F, Gonçalves D and Oliveira RF (2017). Social network predicts loss of fertilizations in nesting males of a fish with alternative reproductive tactics. Acta Ethologica 20: 59-68. doi: 10.1007/s10211-016-0249-9
- Teles MC, Cardoso SD and Oliveira RF (2016). Social Plasticity Relies on Different Neuroplasticity Mechanisms across the Brain Social Decision-Making Network in Zebrafish. Frontiers in Behavioral Neuroscience 10: 16. doi: 10.3389/fnbeh.2016.00016
- Cardoso SD, Teles MC and Oliveira RF (2015). Neurogenomic mechanisms of social plasticity. Journal of Experimental Biology 218: 140-149. doi: 10.1242/jeb.106997
- Cardoso SD, Gonçalves D, Robalo JI, Almada VC, Canario AVM and Oliveira RF (2013). Efficient isolation of polymorphic microsatellites from high-throughput sequence data based on number of repeats. Marine Genomics 11: 11-16. doi: 10.1016/j.margen.2013.04.0022
SELECTED COMMUNICATIONS
- Cardoso SD, Lau I.H., Gonçalves D. “Sex-specific differences in behaviour after exposure to microplastics in the marine medaka Oryzias melastigma”. Poster presentation at the Society for Social Neuroscience (S4SN2024) meeting, March 25-28, 2024, Tsukuba International Congress Center, Tsukuba, Japan.
- Cardoso SD, Ramos A, Gonçalves D. “Fighting behaviour in Siamese fighting fish (Betta splendens): influence of gonadectomy on aggression and hormone levels”. Society of Behavioral Neuroendocrinology (SBN) Meeting. Université de Tours, Tours, France. June 26-29, 2023.
- Cardoso SD, Ramos A, Louro B, Canário AVM and Gonçalves D. “Divergent neurogenomic response to aggression in male and female Siamese fighting fish”, contributed talks session 6 – Sexual selection and conflict, Genetics and Genomics. Association for the Study of Animal Behaviour (ASAB) Winter 2020 Virtual meeting. December 3-4, 2020.
- Cardoso SD, Ramos A, Gonçalves D. Unravelling the neurogenomic basis of aggression in males and females of the Siamese fighting fish Betta splendens. Poster no. A38 at the Society for Social Neuroscience (S4SN) 10th Anniversary Meeting. October 17-18, 2019. Museum of Science and Industry, Chicago, IL, USA.
- Cardoso SD, Gonçalves D, Saraiva J, Goesmann A, Canário AVM and Oliveira, RF. “Alternative reproductive tactics and sex role reversal in the peacock blenny Salaria pavo, a transcriptomic analysis”, contributed talks session 4 – Genes and Behaviour (CT4.4). Behaviour 2017: joint meeting of the 35th International Ethological Conference (IEC) and the 2017 Summer Meeting of the Association for the Study of Animal Behaviour (ASAB). July 30 to August 4, 2017. Estoril Congress Center, Estoril, Portugal.